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安成才

郵  箱: chcaian (AT) pku.edu.cn

職  稱:教授

  • 個人簡介
  • 科研領域
  • 代表性論文

教育經曆:

1989 - 1992 , 理學博士 , 植物分子生物學 , 日本崗山大學
1987 - 1989 , 理學碩士 , 植物病理 , 日本三重大學
1977 - 1980 , 畢業 , 植物保護 , 東北林業大學

工作經曆:

2001 - 至今,   教授,       beat365官方网站
1997 - 1998,  訪問學者,    英國牛津大學
1995 - 2001,  副教授,       beat365官方网站
1993 - 1995,  博士後,       北京大學
1992 - 1993,  客座研究員,     日本崗山大學
1982 - 1983,  進修,        武漢大學
1980 - 1985,  任教,        東北林業大學

社會服務工作:

2012 - 至今, 咨詢專家, 中國檢科院 國家檢疫處理與裝備工程技術研究中心
2008 - 2013, 專業委員, 中國植物學會 植物生理及分子生物學
2006 - 至今, 專家, 教育部自然科學獎評審
2003 - 2008, 專家, 國家商務部出口管制專家支持體系

榮譽獎勵:

北京大學首屆産學研合作先進個人獎, 2013
北京大學教學優秀獎, 2004
北京大學桐山獎教金優秀獎, 2001
英國牛津大學訪問學者, 1997
英國De Montfort大學兼職研究員, 1995

執教課程:

植物分子生物學(本科生), 講課, 北京大學, 1998年-暫停
基因表達與調控(研究生), 講課, 北京大學, 1994年-至今 春季學期
      研究興趣:
1、植物抗病免疫反應的分子機理:
(1)植物介導激素信号途徑調控抗病免疫反應的分子機制
(2)植物超敏細胞死亡的信号通路及其調控機理
2、植物營養組織中異位合成與積累三酰甘油(TAG)的代謝轉換調控機制
1. Wu Q, Zhang X, Peirats LM, Belda PB, Wang XF, Cui S, Yu XC, Rodriguezb PL*., An CC*., Ubiquitin Ligases RGLG1 and RGLG5 Regulate Abscisic Acid Signaling by Controlling the Turnover of Phosphatase PP2CA. Plant cell, 2016, doi:10.1105/ tpc.16.00364.
2. Zhang X, Wu Q, Cui S, Ren J, Qian WQ, Yang Y, He SP, Chu JF, Sun XH, Yan CY, Yu XC and An CC*., Hijacking of the jasmonate pathway by the mycotoxin fumonisin B1 (FB1) to initiate programmed cell death in Arabidopsis is modulated by RGLG3 and RGLG4. J. of Exp. Bot., 2015, Vol., 66(9): 2709–2721.
3. Yang L, Li BS, Zheng XY, Li J, Yang M, Dong XN, He GM*, An CC* and Deng XW*, Enhanced Salicylic Acid Biosynthesis Is Involved in Increased Resistance to Biotrophic Bacterial Pathogen in Arabidopsis Hybrids. Nature Communications, 2015, (6:7309), DOI: 10.1038/ncomms8309.
4. Yinfei Kong, Songbin Chen, Yang Yang, and Chengcai An* , ABA-insensitive (ABI) 4 and ABI5 synergistically regulate DGAT1 expression in Arabidopsis seedlings under stress , FEBS Letters , 2013 , Vol., 587:3076–3082.
5. Liwen Fu, Xiangchun Yu, and Chengcai An* , Overexpression of constitutively active OsCPK10 increases Arabidopsis resistance against Pseudomonas syringae pv. tomato and rice resistance against Magnaporthe grisea , Plant Physiology and Biochemistry , 2013, Vol., 73: 202-210.
6. Xu Zhang, Qian Wu, Jiao Ren, Wanqiang Qian, Shanping He, Kuowei Huang, XiangChun Yu, Yin Gao, Ping Huang, and Chengcai An* , Two Novel RING-Type Ubiquitin Ligases, RGLG3 and RGLG4, Are Essential for Jasmonate-Mediated Responses in Arabidopsis , Plant Physiology , 2012 , Vol. 160: 1–15.
7. Xu Zhang, Qian Wu and Chengcai An* , RGLG3 and RGLG4, novel ubiquitin ligases modulating jasmonate signaling , Plant Signaling & Behavior , 2012 , Vol., 7(12):1-3.
8. Shuanglei Kong, Xinyao Liu, Liwen Fu, Xiangchun Yu, Chengcai An* , I-PfoP3I: A Novel Nicking HNH Homing Endonuclease Encoded in the Group I Intron of the DNA Polymerase Gene in Phormidium foveolarum Phage Pf-WMP3 , PLoS ONE , 2012 , Vol: 7(8): e43738.
9. Yang Yang, Xiangchun Yu, Lianfen Song, and Chengcai An* , ABI4 Activates DGAT1 Expression in Arabidopsis Seedlings during Nitrogen Deficiency , Plant Physiology , 2011 , Vol. 156: 873–883.
10. Shanping He, Kuowei Huang, Xu Zhang, Xiangchun Yu, Ping Huang, Chengcai An* , The LSD1-Type Zinc Finger Motifs of Pisum sativa LSD1 Are a Novel Nuclear Localization Signal and Interact with Importin Alpha , PLoS ONE , 2011 , Vol. 6(7): e22131.
11. Yang Yang, Xiangchun Yu, Lianfen Song, and Chengcai An* , Nitrogen Deficiency System is Helpful in Characterizing Regulation Mechanisms of Ectopic Triacylglycerol Accumulation in Arabidopsis Seedlings , Plant Signaling & Behavior , 2011 , Vol., 6(12):1-2.
12. Shanping He, Guihong Tan, Qian Liu, Kuowei Huang, Jiao Ren, Xu Zhang, Xiangchun Yu, Ping Huang, Chengcai An* , The LSD1-Interacting Protein GILP Is a LITAF Domain Protein That Negatively Regulates Hypersensitive Cell Death in Arabidopsis , PLoS ONE , 2011 , Vol. 6(4): e18750.
13. Jiayu Gu, Ye Wang, Xu Zhang, Shihua Zhang, Yin Gao, Chengcai An* , Identification of gibberellin acid-responsive proteins in rice leaf sheath using proteomics , Frontiers in Bioscience , 2010 , 15: 854-867.
14. CHE NanYing, YANG Yang, LI YanDong, WANG LiLi, HUANG Ping, GAO Yin & An ChengCai* , Efficient LEC2 activation of OLEOSIN expression requires two neighboring RY elements on its promoter , Sci China Ser C-Life Sci , 2009 , 52(9): 854-863.
15. Nanying Che, Lili Wang, Yin Gao, Chengcai An* , Soluble expression and one-step purification of a neurotoxin Huwentoxin-I in Escherichia coli , Protein Expression and Purification , 2009 , 65: 154–159.
16. Xinyao Liu & Shuanglei Kong & Miao Shi & Liwen Fu & Yin Gao & Chengcai An* , Genomic Analysis of Freshwater Cyanophage Pf-WMP3 Infecting Cyanobacterium Phormidium foveolarum: The Conserved Elements for a Phage , Microbial Ecology , 2008 , 56:671-680.
17. Li Xu, Ye Wang, Lijiang Wang, Yin Gao, Chengcai An* , TYchi, a novel chitinase with RNA N-glycosidase and anti-tumor activities , Frontiers in Bioscience , 2008 , 13: 3127-3135.
18. Li Xu, Lijiang Wang, Tao Liu, Wanqiang Qian, Yin Gao, Chengcai An* , Triton, a novel family of miniature inverted-repeat transposable elements (MITEs) in Trichosanthes kirilowii Maximowicz and its effect on gene regulation , BBRC , 2007 , 364: 668-674.
19. Xinyao Liu, Miao Shi, Shuanglei Kong, Yin Gao, Chengcai An* , Cyanophage Pf-WMP4, a T7-like phage infecting the freshwater cyanobacterium Phormidium foveolarum: Complete genome sequence and DNA translocation , Virology , 2007 , 366: 28–39.
20. Tao Liu, Jia-yu Gu, Chen-jia Xu, Yin Gao, Cheng-cai An* , Overproduction of OsSLRL2 alters the development of transgenic Arabidopsis plants , BBRC , 2007 , 358: 983–989.
21. Wanqiang Qian, Guihong Tan, Shanping He, Xinyue Zhang, Xu Zhang, Yin Gao, Hongxia Liu and Chengcai An* , Identification of a new AT-rich-element binding factor PsATF1 and its combined effect with PsGBF on the activation of PsCHS1 promoter , Frontiers in Bioscience , 2007 , Vol. 12: 1670-1679.
22. Wanqiang Qian • Guihong Tan • Hongxia Liu • Shanping He • Yin Gao • Chengcai An* , Identification of a bHLH-type G-box binding factor and its regulation activity with G-box and Box I elements of the PsCHS1 promoter , Plant Cell Rep , 2006 , 23: 85-93.
23. Miao Shi, Li Zou, Xinyao Liu, Yin Gao, Zhongkai Zhang, Weizhong Wu, Donghui Wen, Zhangliang Chen and Chengcai An* , A novel bacterium Saprospira sp. strain PdY3 forms bundles and lyses cyanobacteria , Frontiers in Bioscience , 2006 , 11: 1916-1923.
24. Liu Xinyao, Shi Miao, Liao Yonghong, Gao Yin, Zhang Zhongkai, Wen Donghui, Wu Weizhong and An Chencai* , Feeding Characteristics of an Amoeba (Lobosea: Naegleria) Grazing Upon Cyanobacteria: Food Selection, Ingestion and Digestion Progress , Microbial Ecology , 2006 , 51: 315–325.
25. Xin-Yue Zhang, Ye Wu, Jin-Yuan Yan, Yin Gao, Ye Wang, Shuang-Li Mi, Cheng-Cai An* , Y55 and D78 are crucial amino acid residues of a new IgE epitope on trichosanthin , BBRC , 2006 , 343(4):1251-1256.
26. Ye Wang, Shuang-li Mi, Mei-yan Lou, Yin Gao, Zhang-liang Chen and ChengCai An* , Enhanced green fluorescence protein tracks trichosanthin in human choriocarcinoma cells as a feasible and stable reporter , Frontiers in Bioscience , 2005 , 10, 2279-2284.
27. Wenjie Ji, Xinyue Zhang, Huicong Hu, Jiyuan Chen, Yin Gao, Songping Liang, Chengcai An* , Expression and puriWcation of Huwentoxin-I in baculovirus system , Protein Expression and Purification , 2005 , 41(2):454-458.
28. Guihong Tan, Yin Gao, Miao Shi, Xinyue Zhang, Shanping He, Zhangliang Chen and Chengcai An* , SiteFinding-PCR: a simple and efficient PCR method for chromosome walking , Nucleic Acids Research , 2005 , Vol. 33, No. 13 e122.
29. Shuang-li Mi, Cheng-cai An*, Ye Wang, Ji-yuan Chen, Nan-ying Che, Yin Gao and Zhang-liang Chen , Trichomislin, a novel ribosome-inactivating protein, induces apoptosis that involves mitochondria and caspase-3 , Archives of Biochemistry and Biophysics , 2005 , 434(2): 258-265.
30. L. Wang, C. An*, W. Qian, T. Liu, J. Li, Z. Chen , Detection of the putative cis-region involved in the induction by a Pyricularia oryzae elicitor of the promoter of a gene encoding phenylalanine ammonia-lyase in rice , Plant Cell Rep , 2004 , 22:513–518.
31. Yan Yuanxin, An Chengcai*, Li Li, Gu Jiayu, Tan Guihong and Chen Zhangliang , T-linker Specific Ligation PCR (T-linker-PCR): An advanced PCR technique for chromosome walking or for isolation of tagged DNA ends , Nucleic Acids Research , 2003 , Vol. 31(12): 1-7 e68.
32. Chunyang Zhang, Chengcai An*, Rongying Wang, Yixuan Gong, Hui Ma, Dieyan Chen & Zhangliang Chen , Capillary Electrophoresis and Circular Dichroism Study of Trichosanthin and Its Mutants , Talanta , 2002 , 57: 467-473.
33. Chun-yang ZHANG, Yi-xuan GONG, Hui MA*, Cheng-cai AN*, Die-yan CHEN and Zhang-liang CHEN , Reactive oxygen species involved in trichosanthin-induced apoptosis of human choriocarcinoma cells , Biochem. J. , 2001 , 355, 653-661.

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