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何光明

郵  箱: heguangming (AT) pku.edu.cn

職  稱:副研究員

辦公室電話:62765487

辦公室地址:北京市海澱區頤和園路5号,北京大學,王克桢樓,100871

所屬實驗室:鄧興旺實驗室

實驗室電話:62766648

實驗室地址:北京市海澱區頤和園路5号,北京大學,王克桢樓,100871

  • 個人簡介
  • 科研領域
  • 代表性論文

教育經曆:

2003.8 - 2006.7 , 理學博士 , 遺傳學 , 複旦大學
2000.9 - 2003.7 , 農學碩士 , 作物遺傳育種 , 中國農業大學
1990.9 - 1994.6 , 理學學士 , 生物技術 , 東北農業大學

工作經曆:

2010.7 - 至今 , 副研究員 , 北京大學
2009.1 - 2010.6 , 博士後 , 美國耶魯大學
2006.8 - 2008.12 , 研究助理 , 北京生命科學研究所
1994.7 - 2000.8 , 研究實習員 , 湖北省農業科學院

書籍編撰:

鄧興旺(主編),李磊,鐘上威,何光明(執行主編).《植物的身體》.商務出版社,2020年4月出版.
      植物雜種優勢形成的分子機制
  植物雜種優勢通常最明顯地表現在與親本相比,雜交子一代在生長或生物量上的優勢。細胞是生物體行使功能的最基本單元,細胞分裂和周期的調控通過影響細胞數量和大小最終決定生長發育和生物量的積累。我們将從細胞層面解析植物生長或生物量雜種優勢形成的分子機制,并進一步探讨其與産量雜種優勢之間的關系。
  植物生長發育與免疫反應之間往往存在着動态平衡關系,植物激素調控網絡在其中起重要作用。我們還将從生物脅迫響應相關植物激素通路及其與促生長類植物激素通路之間的交叉會話出發,深入探讨植物抗病雜種優勢的分子機制及其與生長雜種優勢之間的關系。
*Corresponding author
1. Xu, M., Wang, X., Liu, J., Jia, A., Xu, C., Deng, X.W.* and He, G.* (2022). Natural variation in the transcription factor REPLUMLESS contributes to both disease resistance and plant growth in Arabidopsis. Plant Commun: 100351.
2. Liu, W., Zhang, Y., He, H., He, G.* and Deng, X.W.* (2022). From hybrid genomes to heterotic trait output: Challenges and opportunities. Curr Opin Plant Biol 66: 102193.
3. Yang, L., Liu, P., Wang, X., Jia, A., Ren, D., Tang, Y., Tang, Y., Deng, X.W.* and He, G.* (2021). A central circadian oscillator confers defense heterosis in hybrids without growth vigor costs. Nat Commun 12(1): 2317.
4. Liu, W., He, G.* and Deng, X.W.* (2021). Biological pathway expression complementation contributes to biomass heterosis in Arabidopsis. Proc Natl Acad Sci U S A 118(16).
5. Lin, Z., Qin, P., Zhang, X., Fu, C., Deng, H., Fu, X., Huang, Z., Jiang, S., Li, C., Tang, X., Wang, X., He, G., Yang, Y., He, H., and Deng, X.W. (2020). Divergent selection and genetic introgression shape the genome landscape of heterosis in hybrid rice. Proc Natl Acad Sci U S A 117, 4623-4631.
6. Wang, X., Yang, M., Ren, D., Terzaghi, W., Deng, X.W.*, and He, G.* (2019). Cis-regulated alternative splicing divergence and its potential contribution to environmental responses in Arabidopsis. Plant J 97, 555-570.
7. Ren, D., Wang, X., Yang, M., Yang, L., He, G.*, and Deng, X.W.* (2019). A new regulator of seed size control in Arabidopsis identified by a genome-wide association study. New Phytol 222 895-906.
8. Yang, M., Wang, X., Ren, D., Huang, H., Xu, M., He, G.*, and Deng, X.W.* (2017). Genomic architecture of biomass heterosis in Arabidopsis. Proc Natl Acad Sci U S A 114, 8101-8106.
9. Yang, L., Li, B., Zheng, X.Y., Li, J., Yang, M., Dong, X., He, G.*, An, C.*, and Deng, X.W.* (2015). Salicylic acid biosynthesis is enhanced and contributes to increased biotrophic pathogen resistance in Arabidopsis hybrids. Nat Commun 6, 7309.
10. Wang, Y., Wang, X., Deng, W., Fan, X., Liu, T.T., He, G., Chen, R., Terzaghi, W., Zhu, D., and Deng, X.W. (2014). Genomic features and regulatory roles of intermediate-sized non-coding RNAs in Arabidopsis. Mol Plant 7, 514-527.
11. Wang, Y., Fan, X., Lin, F., He, G., Terzaghi, W., Zhu, D., and Deng, X.W. (2014). Arabidopsis noncoding RNA mediates control of photomorphogenesis by red light. Proc Natl Acad Sci U S A 111, 10359-10364.
12. Liu, T.T., Zhu, D., Chen, W., Deng, W., He, H., He, G., Bai, B., Qi, Y., Chen, R., and Deng, X.W. (2013). A global identification and analysis of small nucleolar RNAs and possible intermediate-sized non-coding RNAs in Oryza sativa. Mol Plant 6, 830-846.
13. He, G.*, Chen, B., Wang, X., Li, X., Li, J., He, H., Yang, M., Lu, L., Qi, Y., and Deng, X.W.* (2013). Conservation and divergence of transcriptomic and epigenomic variation in maize hybrids. Genome Biol 14, R57.
14. Shen, H., He, H., Li, J., Chen, W., Wang, X., Guo, L., Peng, Z., He, G., Zhong, S., Qi, Y., Terzaghi, W., and Deng, X.W. (2012). Genome-wide analysis of DNA methylation and gene expression changes in two Arabidopsis ecotypes and their reciprocal hybrids. Plant Cell 24, 875-892.
15. He, G., Elling, A.A., and Deng, X.W. (2011). The epigenome and plant development. Annu Rev Plant Biol 62, 411-435.
16. Li, J., Li, G., Gao, S., Martinez, C., He, G., Zhou, Z., Huang, X., Lee, J.H., Zhang, H., Shen, Y., Wang, H., and Deng, X.W. (2010). Arabidopsis transcription factor ELONGATED HYPOCOTYL5 plays a role in the feedback regulation of phytochrome A signaling. Plant Cell 22, 3634-3649.
17. He, G., Zhu, X., Elling, A.A., Chen, L., Wang, X., Guo, L., Liang, M., He, H., Zhang, H., Chen, F., Qi, Y., Chen, R., and Deng, X.W. (2010). Global epigenetic and transcriptional trends among two rice subspecies and their reciprocal hybrids. Plant Cell 22, 17-33.
18. Zha, X., Luo, X., Qian, X., He, G., Yang, M., Li, Y., and Yang, J. (2009). Over-expression of the rice LRK1 gene improves quantitative yield components. Plant Biotechnol J 7, 611-620.
19. Wang, X., Elling, A.A., Li, X., Li, N., Peng, Z., He, G., Sun, H., Qi, Y., Liu, X.S., and Deng, X.W. (2009). Genome-wide and organ-specific landscapes of epigenetic modifications and their relationships to mRNA and small RNA transcriptomes in maize. Plant Cell 21, 1053-1069.
20. Zhang, H., He, H., Chen, L., Li, L., Liang, M., Wang, X., Liu, X., He, G., Chen, R., Ma, L., and Deng, X.W. (2008). A Genome-Wide Transcription Analysis Reveals a Close Correlation of Promoter INDEL Polymorphism and Heterotic Gene Expression in Rice Hybrids. Mol Plant 1, 720-731.
21. He, G., Luo, X., Tian, F., Li, K., Zhu, Z., Su, W., Qian, X., Fu, Y., Wang, X., Sun, C., and Yang, J. (2006). Haplotype variation in structure and expression of a gene cluster associated with a quantitative trait locus for improved yield in rice. Genome Res 16, 618-626.

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