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賀新強

郵  箱: hexq (AT) pku.edu.cn

職  稱:教授

辦公室電話:62757016

辦公室地址:北京市海澱區頤和園路5号,北京大學,金光生命科學大樓,100871

所屬實驗室:賀新強實驗室

實驗室電話:62758421

實驗室地址:北京市海澱區頤和園路5号,北京大學,金光生命科學大樓,100871

  • 個人簡介
  • 科研領域
  • 代表性論文

教育經曆:

2003 - 2003 , 博士後 , 德國Fraunhofer 分子生物學及生态學研究所
1999 - 2001, 博士後,beat365官方网站
1996 - 1999 , 理學博士, 中國科學院植物研究所
1990 - 1993 , 理學碩士 , 山東師範大學
1986 - 1990 , 理學學士 , 陝西師範大學

工作經曆:

2016 至今, 教授 博士生導師 , beat365官方网站
2012 - 2016 , 副教授 博士生導師 , beat365官方网站
2002 - 2012 , 副教授 , beat365官方网站
2006 - 2007 , 芬蘭赫爾辛基大學, 訪問學者
2001 - 2002 , 講師 , beat365官方网站
1993 - 1996 , 講師, 山東師範大學

執教課程:

植物生物學及實驗, 主講, 本科生, 春季 2007至今
生物學野外實習, 主講, 本科生, 小學期 2001至今
普通生物學及實驗,主講,本科生,春季、秋季 2010年至今
植物發育生物學, 主講, 研究生, 秋季 2008至2020


      木本植物的次生木質部(木材)是維管形成層活動的産物,其形成過程是植物細胞分化的一種複雜類型,包括維管形成層發生、形成層細胞分裂、分化、細胞擴展、次生壁形成和細胞程序化死亡等階段。這個過程由多種外界因素(如光周期、溫度等)、内部因素(如植物激素等)和它們之間的相互作用來控制。本實驗室主要以楊樹為實驗材料,采用剝皮再生創傷系統和整體系統,研究維管形成層活動周期調控及形成層發生、次生木質部細胞分化、次生壁形成和細胞程序死亡的分子機理,為定向改良木材材質提供理論指導。目前研究方向主要有以下兩個方面:
  1.維管形成層發生及次生維管組織模式形成。  
  2.維管形成層活動周期調控機理。
1. Liu C., Li A., Guo Z., Chen N., Wang Y., Tang W., Wu Y., Liu J., Wang Z., Li L*., He X-Q*. 2025. MicroRNA analysis reveals two modules that antagonistically regulate xylem tracheary element development in Arabidopsis. The Plant Cell, 2025, 37, koaf011.
2. Zhang Y, Wang L, Wu Y, Wang D, and He X-Q*. 2024. Gibberellin promotes cambium reestablishment during secondary vascular tissue regeneration after girdling in an auxin-dependent manner in Populus. Journal of Integrative Plant Biology 66:86-102.
3. Wang L, Hou J, Xu H, Zhang Y, Huang R, Wang D, He X-Q*. 2023. The PtoTCP20-miR396d-PtoGRF15 module regulates the secondary vascular development in Populus. Plant Communications 4, 100494. 2.
4. Zhang Y, Wang X, Zhang J*, He X-Q*. 2023. Plant in situ tissue regeneration: dynamics, mechanisms and implications for forestry research. Forestry Research 2023, 3:8.
5. Liu C, Ma D, Wang Z, Chen N,Ma X and He X-Q*. 2022. MiR395c regulates secondary xylem development through sulfate metabolism in Poplar. Frontiers in Plant Science 13:897376. doi: 10.3389/fpls.2022.897376
6. Hou J, Xu H, Fan D, Ran L, Li J, Wu S, Luo K* and He X-Q*. 2020. MiR319a-targeted PtoTCP20 regulates secondary growth via interactions with PtoWOX4 and PtoWND6 in Populus tomentosa. New Phytologist 228:1354–1368.doi:10.1111/nph.16782.
7. Zhang Y, Ji S, Jian N, Zhang K*, He X-Q*, Duan H*. 2020. Caudicles in vandoid orchids: A carotenoid-based soft material with unique properties. Acta Biomaterialia 113: 478-487.
8. Lin W, Sun L, Huang R-Z, Liang W, Liu X, He H, Fukuda H, He X-Q*, Qian W*. 2020. Active DNA demethylation regulates tracheary element differentiation in Arabidopsis. Science Advances 6 (26), eaaz2963. DOI: 10.1126/sciadv.aaz2963.
9. Chen J-J, Wang L-Y, Immanen J, Nieminen K, Spicer R, Helariutta Y, Zhang J* and He X-Q*. 2019. Differential regulation of auxin and cytokinin during the secondary vascular tissue regeneration in Populus trees. New Phytologist 224: 188-201.
10. Jin F, Li J, Ding Q, Wang QS, He X-Q*. 2017. Proteomic analysis provides insights into changes in the central metabolism of the cambium during dormancy release in poplar. Journal of Plant Physiology 208: 26-39.
11. He X-Q, Groover A. 2017. The genomics of wood formation in angiosperm trees. In A.T. Groover and Q.C.B. Cronk (eds.), Comparative and Evolutionary Genomics of Angiosperm Trees, Plant Genetics and Genomics: Crops and Models. Springer International Publishing AG 2017. DOI 10.1007/7397_2016_17.
12. Liu JD, Hou J, Chen HM, Pei KL, Li Y, He X-Q*. 2017. Dynamic changes of pectin epitopes in cell walls during the development of the procambium-cambium continuum in poplar. International Journal of Molecular Science 18, 1716; doi:10.3390/ijms 18081716.
13. He X-Q, Qu LJ. 2016. Cellular and molecular features of the procambium and cambium in plant vascular tissue development. In Ray J. Rose (ed.), Molecular Cell Biology of the Growth and Differentiation of Plant Cells. CRC Press, Taylor & Francis Group, LLC. P236-256.
14. Zeng J, Ding Q, Fukuda H, He X-Q*. 2016. Fertilization Independent Endosperm genes repress NbGH3.6 and regulate the auxin level during shoot development in Nicotiana benthamiana. Journal of Experimental Botany 67:2207-2217.
15. Ding Q, Zeng J, He X-Q*. 2016. MiR169 and its target PagHAP2-6 regulated by ABA are involved in poplar cambium dormancy. Journal of Plant Physiology 198: 1–9.
16. Ding Q, Zeng J, He X-Q*. 2014. Deep sequencing on a genome-wide scale reveals diverse stage-specific microRNAs in cambium during dormancy-release induced by chilling in poplar. BMC Plant Biology 14:267.
17. Chen JJ, Zhang J, He X-Q*. 2014. Tissue regeneration after bark girdling: an ideal research tool to investigate plant vascular development and regeneration. Physiologia Plantarum 151: 147-155.
18. Li WF, Ding Q, Cui KM, He X-Q*. 2013. Cambium reactivation independent of bud unfolding involves de novo IAA biosynthesis in cambium regions in Populus tomentosa Carr. Acta Physiologia Plantarum 35: 1827-1836.
19. Lucas WJ, Groover A, Lichtenberger R, Furuta K, Yadav SR, Helariutta Y, He X-Q, Fukuda H, Kang J, Brady SM, Patrick JW, Sperry J, Yoshida A, Lopez-Millan AF, Grusak M,Kachroo P. 2013. The Plant Vascular System: Evolution, Development and Functions. Journal of Integrative Plant Biology 55: 294–388.
20. Han JJ, Lin W, Oda Y, Cui KM, Fukuda H, He X-Q*. 2012. The proteasome is responsible for caspase-3-like activity during xylem development. The Plant Journal 72, 129–141.
21. Zhao L, Ding Q, Zen Jung, Wang FR, Zhang J, Fan SJ*, He X-Q*. 2012. An improved CTAB– ammonium acetate method for total RNA isolation from cotton. Phytochemical Analysis 23: 647-650.
22. Chen HM, Pang Y, Zeng J, Ding Q, Yin SY, Liu C, Lu MZ, Cui KM, He X-Q*. 2012. The Ca2+ dependent DNases are involved in secondary xylem development in Eucommia ulmoides. Journal of Integrative Plant Biology 54 (7): 456–470.
23. Zhang J, Gao G, Chen JJ, Taylor G, Cui KM and He X-Q*. 2011. Molecular features of secondary vascular tissue regeneration after bark girdling in Populus. New Phytologist 192: 869-884.
24. Chen HM, Han JJ, Cui KM, He X-Q*. 2010. Modification of cambial cell wall architecture during cambium periodicity in Populus. Trees 24: 533-540.
25. Li WF, Cui KM, He X-Q*. 2009. Regulation of cell cycle regulators by environmental signals during growth-dormancy cycle of trees. Plant Signaling & Behavior 4(10): 959-961
26. Li WF, Ding Q, Chen JJ, Cui KM, He X-Q*. 2009. Induction of PtoCDKB and PtoCYCB transcription by temperature during cambium reactivation in Populus. Journal of Experimental Botany 60: 2621–2630
27. Pang Y, Zhang J, Cao J, Yin SY, He X-Q*, Cui KM*. 2008. Phloem Transdifferentiation from Immature Xylem Cells during Bark Regeneration after Girdling in Eucommia ulmoides Oliv. Journal of Experimental Botany 59: 1341-1351

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