個人介紹:

秦跟基，beat365官方网站教授、國家傑出青年科學基金獲得者，長期緻力于植物發育生物學研究，現任北京大學基因功能研究與操控全國重點實驗室副主任。所領導的研究團隊以大豆和拟南芥為材料，運用前沿的分子遺傳學、生物化學及分子生物學技術，研究植物器官可塑性發育。成功克隆了多個調控植物器官發育的關鍵基因，揭示了TCP、EXB1、TIE1和TEAR1等轉錄因子在葉片、分枝、雌蕊及種子發育中的重要功能及核心調控機制；系統闡明了轉錄因子、轉錄調控因子與E3泛素連接酶之間的相互作用機制，為理解植物器官可塑性發育的分子基礎提供了全新視角。其中，關于TCP轉錄因子新功能的發現，不僅拓展了學界對這一重要基因家族的認知，更為農作物分子設計育種奠定了重要的理論基礎。在Nature Communications、Molecular Plant、Science Advances、Advanced Science、Plant Cell、PNAS、Cell Research、New Phytologist等國際主流期刊發表論文40餘篇，累計被引用超過5000次。參與主譯了《植物生物學》和《植物生物化學與分子生物學》經典教材。任中國植物學會植物結構與生殖生物學專業委員會副主任、北京市植物學會理事。展望未來，本團隊将繼續深耕植物發育生物學研究，解析植物生長發育的奧秘，通過馴化改良大豆關鍵農藝性狀，服務國家糧食安全重大戰略。

教育經曆:

2007 - 2009, 訪問學者 , 生物科學系 , 美國加州大學聖地亞哥分校
2001 - 2003, 博士後 , beat365官方网站
1996 - 2001, 畢業 , 植物遺傳育種 , 南京農業大學農學院，農學博士
1992 - 1996, 畢業 , 植物遺傳育種 , 南京農業大學農學院，農學學士

工作經曆:

2015 - 至今，教授，beat365官方网站
2006 - 2015，副教授，beat365官方网站
2001 - 2006， 講師，beat365官方网站

社會服務工作:

北京大學研究生教育委員會委員
北京大學生命科學學位分會委員
beat365官方网站安全管理委員會委員

榮譽獎勵:

北京大學教學優秀獎, 2022
beat365官方网站東寶獎教金，2021
北京大學北京銀行教師獎，2020
北京大學博雅特聘教授, 2018
北京大學綠葉生物醫藥傑出青年學者獎，2012
教育部新世紀優秀人才，2010

學術任職:

中國植物學會植物結構與生殖生物學專業委員會副主任
北京市植物學會理事

評審任職:

國家自然科學基金、教育部學位中心以及包括Nature Communications、The Plant Cell等多個專業雜志的同行評審專家。

教材編撰:

《植物生物學》

執教課程:

學位論文寫作規範，必修，北京大學，春季學期
博士論文寫作讨論和指導，必修，北京大學，春季學期
植物生物學研究前沿，必修，北京大學，秋季和春季學期

      聚焦植物發育生物學前沿領域，緻力于解析植物器官可塑性發育的分子調控網絡及其在農業中的應用。以大豆和拟南芥為模式系統，通過整合分子遺傳學、生物化學與多組學技術，揭示植物器官可塑性發育的核心轉錄調控規律和分子機制，聚焦研究大豆關鍵農藝性狀的分子馴化，破解環境适應性與産量協同提升的遺傳密碼，助力國家糧食安全與可持續農業發展。

1. Yutao Wang, Yu Cao, Genji Qin* (2025) Multifaceted roles of TCP transcription factors in fate determination. New Phytologist 245(1):95-101.
2. Hao Yu, Yutao Wang, Yi Wang, Xing Wang Deng, Genji Qin* (2024) The Arabidopsis RING-type E3 ligase TEAR4 controls seed germination by targeting RGA for degradation. Advanced Science e2400116.
3. Yutao Wang, Ning Wang, Jingqiu Lan, Yige Pan, Yidan Jiang, Yongqi Wu, Xuemei Chen, Xianzhong Feng, Genji Qin* (2024) Arabidopsis transcription factor TCP4 controls the identity of the apical gynoecium. Plant Cell 36(7):2668-2688.
4. Yuxing Fang, Dongshu Guo, Yi Wang, Ning Wang, Xianwen Fang, Yunhui Zhang, Xiao Li, Letian Chen, Diqiu Yu, Baolong Zhang*, Genji Qin* (2024) Rice transcriptional repressor OsTIE1 controls anther dehiscence and male sterility by regulating JA biosynthesis. Plant Cell 36(5):1697-1717.
5. Jingqiu Lan, Ning Wang, Yutao Wang, Yidan Jiang, Hao Yu, Xiaofeng Cao, Genji Qin* (2023) Arabidopsis TCP4 transcription factor inhibits high temperature-induced homeotic conversion of ovules. Nature Communications 14(1):5673.
6. Wenqi Qin, Ning Wang, Qi Yin, Huiling Li, Ai-Min Wu and Genji Qin* (2022) Activation tagging identifies WRKY14 as a repressor of plant thermomorphogenesis in Arabidopsis. Molecular Plant 15(11):1725-1743.
7. Qing He, Rongrong Yuan, Tiantian Zhang, Fengying An, Ning Wang, Jingqiu Lan, Xinxue Wang, Zeliang Zhang, Yige Pan, Xuanzhi Wang, Jinzhe Zhang, Dongshu Guo and Genji Qin* (2022) Arabidopsis TIE1 and TIE2 transcriptional repressors dampen cytokinin response during root development. Science Advances 8(36): eabn5057.
8. Xinhui Zheng, Jingqiu Lan, Hao Yu, Jingzhe Zhang, Yi Zhang, Yongmei Qin, Xiao-Dong Su and Genji Qin* (2022) Arabidopsis transcription factor TCP4 represses chlorophyll biosynthesis to prevent petal greening. Plant Communications 4: 100309.
9. Jingqiu Lan, Jinzhe Zhang, Rongrong Yuan, Hao Yu, Linhua Sun, Fengying An, Haodong Chen, Yue Zhou, Weiqiang Qian, Hang He and Genji Qin* (2021) TCP transcription factors suppress cotyledon trichomes by impeding a cell differentiation-regulating complex. Plant Physiology 186: 434-451.
10. Jingqiu Lan and Genji Qin* (2020) The regulation of CIN-like TCP transcription factors. International Journal of Molecular Sciences 21: 4498.
11. Xiang Han, Hao Yu, Rongrong Yuan, Yan Yang, Fengying An, Genji Qin* (2019) Arabidopsis transcription factor TCP5 controls plant thermomorphogenesis by positively regulating PIF4 activity. iScience 15: 611-622.
12. Rongrong Yuan, Jingqiu Lan, Yuxing Fang, Hao Yu, Jinzhe Zhang, Jiaying Huang and Genji Qin* (2018) The Arabidopsis USL1 controls multiple aspects of development by affecting late endosome morphology. New Phytologist 219: 1388-1405.
13. Yan Yang#, Michael Nicolas#, Jinzhe Zhang, Hao Yu, Dongshu Guo, Rongrong Yuan, Tiantian Zhang, Jianzhao Yang, Pilar Cubas*, Genji Qin* (2018) The TIE1 transcriptional repressor controls shoot branching by directly repressing BRANCHED1 in Arabidopsis. PLoS Genetics 14(3): e1007296.
14. Jinzhe Zhang, Baoye Wei, Rongrong Yuan, Jianhui Wang, Mingxin Ding, Zhuoyao Chen, Hao Yu, Genji Qin* (2017). The Arabidopsis RING-type E3 ligase TEAR1 controls leaf development by targeting the TIE1 transcriptional repressor for degradation. Plant Cell 29(2): 243-259.
15. Dongshu Guo, Genji Qin* (2016). EXB1/WRKY71 transcription factor regulates both shoot branching and responses to abiotic stresses. Plant Signaling & Behavior. 11(3): e1150404.
16. Shibai Li, Xiaochen Wang, Shan He, Jieru Li, Qingpei Huang, Takato Imaizumi, Leqing Qu, Genji Qin, Li-Jia Qu, and Hongya Gu* (2016). CFLAP1 and CFLAP2 Are Two bHLH Transcription Factors Participating in Synergistic Regulation of AtCFL1-Mediated Cuticle Development in Arabidopsis. PLoS Genetics. 12(1): e1005744.
17. Dongshu Guo, Jinzhe Zhang, Xinlei Wang, Xiang Han, Baoye Wei, Jianqiao Wang, Boxun Li, Hao Yu, Qingpei Huang, Hongya Gu, Li-Jia Qu, Genji Qin* (2015). The WRKY transcription factor WRKY71/EXB1 controls shoot branching by transcriptionally regulating RAX genes in Arabidopsis. Plant Cell 27: 3112-3127. (cover story)
18. Qing Liu, Gezhi Shen, Keqin Peng, Zhigang Huang, Jianhua Tong, Mohammed Humayun Kabir, Jianhui Wang, Jingzhe Zhang, Genji Qin* and Langtao Xiao* (2015). The alteration in the architecture of a T-DNA insertion rice mutant osmtd1 is caused by up-regulation of MicroRNA156f. Journal of Integrative Plant Biology 57(10):819-829.
19. Baoye Wei, Jinzhe Zhang, Changxu Pang, Hao Yu, Dongshu Guo, Hao Jiang, Mingxin Ding, Zhuoyao Chen, Qing Tao, Hongya Gu, Li-Jia Qu, Genji Qin* (2015). The molecular mechanism of SPOROCYTELESS/NOZZLE in controlling Arabidopsis ovule development. Cell Research 25:121-134.
20. Yan Yang, Bin Ou, Jinzhe Zhang, Hongya Gu, Genji Qin and Li-Jia Qu (2014). The Arabidopsis Mediator subunit MED16 regulates iron homeostasis by associating with EIN3/EIL1 through subunit MED25. Plant Journal 77(6):838-851.
21. Ruixi Li, Jieru Li, Shibai Li, Genji Qin, Ondrej Novak, Ales Pencik, Karin Ljung，Takashi Aoyama, Jingjing Liu, Angus Murphy, Hongya Gu, Tomohiko Tsuge, Li-Jia Qu (2014). ADP1 Affects Plant Architecture by Regulating Local Auxin Biosynthesis. PLOS Genetics 10(1): e1003954.
22. Jin Miao#, Dongshu Guo#, Jinzhe Zhang#, Qingpei Huang#, Genji Qin#, Xin Zhang,Jianmin Wan, Hongya Gu, Li-Jia Qu* (2013). Targeted mutagenesis in rice using CRISPR-Cas system. Cell Research 23(10):1233-1236.
23. Tong Wei, Bin Ou, Jinbin Li, Yang Zhao, Dongshu Guo, Youyong Zhu, Zhangliang Chen, Hongya Gu, Chengyun Li*, Genji Qin* and Li-Jia Qu* (2013). Transcriptional profiling of rice early response to Magnaporthe oryzae identified OsWRKYs as important regulators in rice blast resistance. PLoS ONE 8(3): e59720.
24. Qing Tao, Dongshu Guo, Baoye Wei, Fan Zhang, Changxu Pang, Hao Jiang, Jinzhe Zhang, Tong Wei, Hongya Gu, Li-Jia Qu, Genji Qin* (2013). The TIE1 Transcriptional Repressor Links TCP Transcription Factors with TOPLESS/TOPLESS-RELATED Corepressors and Modulates Leaf Development in Arabidopsis. Plant Cell 25: 421-437
25. Yan Chen, Zhangliang Chen, Juqing Kang, Dingming Kang, Hongya Gu, Genji Qin* (2013). AtMYB14 Regulates Cold Tolerance in Arabidopsis. Plant Molecular Biology Reporter 31: 87-97.
26. Mingqiu Dai, Chen Zhang, Urszula Kania, Fang Chen, Qin Xue, Tyra Mccray, Gang Li, Genji Qin, Michelle Wakeley, William Terzaghi, ,Jianmin Wan, Yunde Zhao, Jian Xu, Jiří Friml, Xing Wang Deng and Haiyang Wang (2012). A novel PP6-type phosphatase holoenzyme directly regulates PIN phosphorylation and auxin efflux in Arabidopsis. Plant Cell 24: 2497-2514.
27. Wei-ying Wang, Li Zhang, Shufan Xing, Zhiqiang Ma, Jingjing Liu, Hongya Gu, Genji Qin* and Li-jia Qu* (2012). Arabidopsis AtVPS15 plays essential roles in pollen germination possibly by interacting with AtVPS34. Journal of Genetics and Genomics 39: 81-92.
28. Yang Zhao, Tong Wei, Kang-Quan Yin, Zhangliang Chen, Hongya Gu, Li-Jia Qu and Genji Qin*（2012）. Arabidopsis RAP2.2 plays an important role in plant resistance to Botrytis cinerea and ethylene responses. New Phytologist 195: 450-460.
29. Renhong Wu, Shibai Li, Shan He, Friedrich Waßmann, Caihong Yu, Genji Qin, Lukas Schreiber, Li-Jia Qu, and Hongya Gu (2011). CFL1, a WW domain protein, regulates cuticle development by modulating the function of HDG1, a Class IV homeodomain transcription factor, in rice and Arabidopsis. Plant Cell 23(9): 3392-3411.
30. Yu Luo, Genji Qin, Jun Zhang, Yuan Liang,Yingqi Song,Meiping Zhao,Tomohiko Tsuge,Takashi Aoyama,Jingjing Liu,Hongya Gu, and Li-Jia Qu (2011). D-myo-Inositol-3-Phosphate Affects Phosphatidylinositol-Mediated Endomembrane Function in Arabidopsis and Is Essential for Auxin-Regulated Embryogenesis. Plant Cell 23(4): 1352-72.
31. Yanxia Zhang, Renhong Wu, Genji Qin, Zhangliang Chen, Hongya Gu, Li-Jia Qu (2011). Over-expression of WOX1 leads to defects in meristem development and polyamine homeostasis in Arabidopsis. Journal of Integrative Plant Biology 53: 493-506.
32. Lihua Han, Genji Qin, Dingming Kang, Zhangliang Chen, Hongya Gu, Li-Jia Qu （2010）. A nuclear-encoded mitochondrial gene AtCIB22 is essential for plant development in Arabidopsis. Journal of Genetics and Genomics 37: 667-683.
33. Shufan Xing, Jin Miao, Shuang Li, Genji Qin, Si Tang, Haoni Li, Hongya Gu, Li-Jia Qu, (2010) Disruption of the 1-deoxy-D-xylulose-5-phosphate reductoisomerase (DXR) results in albino, dwarf and defects in trichome initiation and stomata closure in Arabidopsis. Cell Research 20:688-700.
34. Yong Guo, Genji Qin, Hongya Gu, and Li-Jia Qu (2009). Dof5.6/HCA2, a Dof transcription factor gene, regulates interfascicular cambium formation and vascular tissue development in Arabidopsis. Plant Cell 21: 3518-3534.
35. Jingjing Liu, Yiyue Zhang, Genji Qin, Tomohiko Tsuge, Norihiro Sakaguchi, Guo Luo, Kangtai Sun, Dongqiao Shi, Shiori Aki, Nuoyan Zheng, Takashi Aoyama, Atsuhiro Oka, Weicai Yang, Masaaki Umeda, Qi Xie, Hongya Gua, and Li-Jia Qu, (2008). Targeted Degradation of the Cyclin-Dependent Kinase Inhibitor ICK4/KRP6 by RING-Type E3 Ligases Is Essential for Mitotic Cell Cycle Progression during Arabidopsis Gametogenesis. Plant Cell 20: 1538-1554.
36. Youfa Cheng, Genji Qin, Xinhua Dai, and Yunde Zhao (2008). NPY genes and AGC kinases define two key steps in auxin-mediated organogenesis in Arabidopsis. Proceedings of the National Academy of Sciences, USA 105 (52): 21017-21022.
37. Lin-Chuan Li#, Genji Qin#, Tomohiko Tsuge, Xian-Hui Hou, Mao-Yu Ding, Takashi Aoyama,Atsuhiro Oka, Zhangliang Chen, Hongya Gu, Yunde Zhao and Li-Jia Qu (2008). aSPOROCYTELESS modulates YUCCA expression to regulate the development of lateral organs in Arabidopsis. New Phytologist 179(3): 751-764. (co-first author).
38. Xin Li, Genji Qin, Zhangliang Chen, Hongya Gu, and Li-Jia Qu (2008). A gain-of-function mutation of transcriptional factor PTL results in curly leaves, dwarfism and male sterility by affecting auxin homeostasis. Plant Molecular Biology 66: 315-327.
39. Youfa Cheng#, Genji Qin#, Xinhua Dai, and Yunde Zhao (2007). NPY1, a BTB-NPH3-like protein, plays a critical role in auxin-regulated organogenesis in Arabidopsis. Proceedings of the National Academy of Sciences, USA 104(47): 18825-18829 (co-first author).
40. Shufan Xing, Genji Qin, Yan Shi, Zhiqiang Ma, Zhangliang Chen, Hongya Gu and Li-Jia Qu (2007). GAMT2 encodes a methyltransferase of gibberellic acid that is involved in seed maturation and germination in arabidopsis. Journal of Integrative Plant Biology 49 (3): 368-381.
41. Genji Qin, Hongya Gu, Ligeng Ma, Yiben Peng, Xing Wang Deng, Zhangliang Chen, Li-Jia Qu (2007). Disruption of phytoene desaturase gene results in albino and dwarf phenotypes in Arabidopsis by impairing chlorophyll, carotenoid, and gibberellin biosynthesis. Cell Research 17:471-482.
42. Genji Qin, Zhiqiang Ma, Li Zhang, Shufan Xing, Xianhui Hou, Jie Deng, Jingjing Liu, Zhangliang Chen, Li-Jia Qu, Hongya Gu (2007). Arabidopsis AtBECLIN 1/AtAtg6/AtVps30 is essential for pollen germination and plant development. Cell Research 17: 249-263.
43. Genji Qin, Hongya Gu, Yunde Zhao, Zhiqiang Ma, Guanglu Shi, Yue Yang, Eran Pichersky, Haodong Chen, Meihua Liu, Zhangliang Chen, and Li-Jia Qu. (2005). An indole-3-acetic acid carboxyl methyltransferase regulate Arabidopsis leaf development. Plant Cell, 17:2693-2704.
44. Gaofeng Jia, Peidu Chen, Genji Qin, Guihua Bai, Xiue Wang, Suling Wang, Bo Zhou, Shouzhong Zhang, Dajun Liu (2005). QTLs for Fusarium head blight response in a wheat DH population of Wangshuibai/Alondra‘s’. Euphytica, 146: 183-191.
45. Genji Qin, Dingming Kang, Yiyu Dong, Yunping Shen, Li Zhang, Xiaohui Deng, Yao Zhang, Song Li, Nan Chen, Weiran Niu, Cong Chen, Peicheng Liu, Haodong Chen, Jigang Li, Yanfei Ren, Hongya Gu, Xingwang Deng, Li-Jia Qu and Zhangliang Chen (2003). Obtaining and analysis of flanking sequences from T-DNA transformants in Arabidopsis. Plant Science, 165: 941-949.